Last edited by Brasida
Tuesday, May 5, 2020 | History

3 edition of Molecular imaging for integrated medical therapy and drug development found in the catalog.

Molecular imaging for integrated medical therapy and drug development

by Nagara Tamaki

  • 225 Want to read
  • 38 Currently reading

Published by Springer in Tokyo .
Written in English

    Subjects:
  • Molecular Imaging,
  • Molecular radiobiology,
  • Cancer,
  • Radiobiology,
  • Drug development,
  • Radiotherapy,
  • Brain,
  • Regenerative Medicine,
  • Drug Discovery,
  • Physiology,
  • Methods

  • Edition Notes

    Includes bibliographical references and index.

    StatementN. Tamaki, Y. Kuge (eds.).
    Classifications
    LC ClassificationsRM847 .M72 2010
    The Physical Object
    Paginationxxi, 303 p. :
    Number of Pages303
    ID Numbers
    Open LibraryOL25279399M
    ISBN 104431980733, 4431980741
    ISBN 109784431980735, 9784431980742
    LC Control Number2009933272
    OCLC/WorldCa551341074

    Comprehensive molecular imaging centers have been established in the US, Europe, and Asia and are increasingly integrated into basic sciences and translational networks. New investigators, collaborators, and students drawn into this multidisciplinary field have often expressed the desire and need for an authoritative textbook. Further development of the use of molecular imaging to predict or assess treatment response must address spatial heterogeneity of cancer within the body. A combination of different imaging modalities should be used to relate the effect of the drug to dosing regimen or effective drug concentration at the local site of by:

      Imaging, including its use for innovative tissue sampling, is slowly being recognized as playing a pivotal role in drug development, clinical trial design, and more effective delivery and monitoring of molecular therapies. The challenge is that, while a considerable number of new imaging technologies and new targeted tracers have been developed for cancer imaging in recent years, the Cited by:   Imaging can provide information on drug behavior in vivo, whole-body drug target visualization, and heterogeneity in drug target expression. This review focuses on current applications of molecular imaging in the development of small molecules, antibodies, and antihormonal anticancer by: 6.

    1. Introduction. Molecular imaging is rapidly gaining recognition as a tool that has the capacity to improve every facet of cancer care. The growing demand among physicians, patients, and society for personalized care is increasing the importance of molecular imaging and shaping the development of biomedical imaging as a by:   The main goal in the emerging field of cancer nanomedicine is to generate, standardize, and produce multifunctional carriers designed to improve the response of drugs against tumors. Here we report the design, development, and preclinical validation of a ligand-directed bioinorganic platform that integrates tumor targeting, receptor-mediated cell internalization, photon-to-heat conversion, and Cited by:


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Molecular imaging for integrated medical therapy and drug development by Nagara Tamaki Download PDF EPUB FB2

Molecular imaging plays an important role in drug discovery and advanced medical practice. A symposium of world leaders in drug research and development, molecular imaging, and medical therapy including regenerative treatment and radiation therapy has led to the publication of this book.

Abstract Molecular imaging plays an important role in drug discovery and advanced medical practice. A symposium of world leaders in drug research and development, molecular imaging, and medical. This book will be of great value to a wide variety of researchers in the fields of drug development and molecular imaging technologies, leading to integrated medical therapy and progress in human Edition: 1st Edition.

Molecular Imaging for Integrated Medical Therapy and Drug Development by Nagara Tamaki (Editor), Yuji Kuge (Editor) Paperback, Pages, Published ISBN / ISBN / Pages: Molecular Imaging for Integrated Medical Therapy and Drug Development's journal/conference profile on Publons, with several reviews by several reviewers - working with reviewers, publishers, institutions, and funding agencies to turn peer review into a measurable research output.

This work is devoted to understanding the recent advances in nuclear medicine and molecular imaging technologies along with their application to integrated medical therapy and future drug development. This anthology is based on the international symposium. This work is devoted to understanding the recent advances in nuclear medicine and molecular imaging technologies along with their application to integrated medical therapy and future drug development.

Molecular imaging has the potential to have a significant impact on different phases of drug development, including target expression, compound screening and optimization Cited by: Molecular Imaging for Integrated Medical Therapy and Drug Development Article in Journal of Nuclear Medicine 53(7) June with 4 Reads How we measure 'reads'.

Part 3 (Molecular Imaging in Cell and Molecular Biology) contains chapters dedicated to protein engineering, vectors, and pathways. Part 4 (Applications of Molecular Imaging) summarizes the above advances in different clinical disease entities.

Part 5 (Molecular Imaging in Drug Evaluation) is dedicated to imaging in drug development.4/5(1). This review focuses specifically on the use of molecular imaging which has been increasing applied to improve and accelerate certain pre-clinical steps in drug development including the identification of appropriate therapeutic targets, evaluation of on-target and off-target effects of candidate therapies, assessment of dose response, and the evaluation of drug or biologic biodistribution and Cited by: 4.

Targeted Molecular Imaging covers the development of novel diagnostic approaches that use an imaging probe and agent to noninvasively visualize cellular processes in normal and disease states. It discusses the concept, development, preclinical studies, and, in many cases, translation to 5/5(1).

INTRODUCTION. Molecular imaging is defined as the ability to visualize and quantitatively measure the function of biological and cellular processes in vivo.

1, 2 While anatomical imaging plays a major role in medical imaging for diagnosis, surgical guidance/followup, and treatment monitoring, the rapidly evolving field of molecular imaging promises improvements in specificity and quantitation Cited by: With a strong emphasis on the chemistry of the design of appropriate molecular imaging probes for early cancer detection, therapy-response monitoring, and anti-cancer drug development, the process of translating novel cancer imaging probes from bench to bedside is extensively discussed.

Medical Imaging and Drug Development. and academia in a number of activities that will facilitate the development of new imaging agents and the use of medical imaging during product.

From the reviews: “Topics covered are intended for a sophisticated multidisciplinary audience. serves as an introduction to the expansive field of molecular imaging while developing in the reader an understanding of many of the complexities that allow novel approaches to studying the physiology, biochemistry, and molecular biology of intact living systems.

imaging scientists and Format: Hardcover. The report describes the urgent need to modernize the medical product development process, the Critical Path, to make product development more predictable and less costly. Molecular imaging in drug development for neurological applications is early on in development, allowing for fast-tracking to clinical trials.

As with all drug development projects, there is a need to streamline processes and reduce costs; molecular imaging is Author: Ben Burke. Integration of molecular imaging into drug development: Topics: Anticancer Agents Clinical Research Basic Scientific Principles Therapy Biological Therapy:.

The importance of the immune system in cancer therapy has been reaffirmed by the success of the immune checkpoint blockade. The complex tumor microenvironment and its interaction with the immune system, however, remain mysteries. Molecular imaging may shed light on fundamental aspects of the immune response to elucidate the mechanism of cancer : Madiha Saeed, Zhiai Xu, Bruno G.

De Geest, Huixiong Xu, Haijun Yu. Part 4 (Applications of Molecular Imaging) summarizes the above advances in different clinical disease entities. Part V (Molecular Imaging in Drug Evaluation) is dedicated to imaging in drug development, and Part IV provides chapters on computation, bioinformatics, and modeling.Molecular imaging is a multidisciplinary field applying molecular biology, synthetic chemistry, pharmacology, and image-capture techniques to the use of imaging probes in vivo.

Modern functional imaging technology in drug development efforts, utilizing novel biomarkers against specific molecular targets, highlights the need for robust imaging platforms to provide noninvasive specific endpoints. This integrative approach could therefore streamline biomarker and drug development, although a range of issues need to be overcome in order to enable a broader use of molecular imaging Cited by: 5.